cobas b 221 operator manual

Report this Document Download Now Save Save Roche Cobas B221 - Service Manual For Later 100% (1) 100% found this document useful (1 vote) 648 views 368 pages Roche Cobas B221 - Service Manual Uploaded by Dian Zainal Abidin Description: OK Full description Save Save Roche Cobas B221 - Service Manual For Later 100% 100% found this document useful, Mark this document as useful 0% 0% found this document not useful, Mark this document as not useful Embed Share Print Download Now Jump to Page You are on page 1 of 368 Search inside document Browse Books Site Directory Site Language: English Change Language English Change Language. Systems with a serial number of 5001 or above are cobas b 221 systems. Systems with a serial number up to 5000 are Roche OMNI S systems. Every effort has been made to ensure that all the information contained in this manual is correct at the time of printing. However, Roche Diagnostics GmbH reserves the right to make any changes necessary without notice as part of ongoing product development. Any customer modification to the instrument will render the warranty or service agreement null and void. Software updates are done by Roche Service representatives. The user must be familiar with the function and operation of the instrument to fully understand the processes described here.The contents of this document may not be reproduced in any form or communicated to any third party without the prior written consent of Roche Diagnostics. Every effort is made to ensure its correctness. Subject to change without notice. Trademarks COBAS, COBAS B, LIFE NEEDS ANSWERS, ROCHE OMNI, AUTOQC, ROCHE MICROSAMPLER, COMBITROL, AUTO-TROL and COBAS BGE LINK are trademarks of Roche. The user must be familiar with the function and operation of the instrument to fully understand the processes described here.In addition, a complete index can be found at the end.

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Please be aware that we do not take any responsibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your origin. Sign in Forgot Password. My Bench Close Sign In Not A Member. Sign Up Join MedWrench OK name type Receive Summary Emails. The analyzer's analytical performance, the flexible configuration of parameters and features supported by its intuitive operation and zero maintenance sensors makes cobas b 221 system a valuable and easy to use tool for all Critical Care applications at the Point of Care (i.e. Intensive Care Unit, Emergency Room etc.) as well as in the laboratory. When equipped with an AutoQC module and connected to our data and instrument management IT solution, user interaction with the system can be reduced to an absolute minimum FORUMS View All (3) Ask a New Question 1 Reply -Ekenechukwu Ignatius 7 years ago 7 years ago Roche cobas b221 reagent pack size Reply 1 Reply -PSZ 7 years ago 7 years ago log in By continuing to browse the site you are agreeing to our use of cookies. Please review our Privacy Policy for more details. All Rights Reserved. Timely monitoring of critical newborns can reduce the risk of potentially life-threatening diseases and enhance neonatal care for hyperbilirubinemia.Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates. Discover everything Scribd has to offer, including books and audiobooks from major publishers. Start Free Trial Cancel anytime.

0 cobas b 221 system Brands COBAS, COBAS B, LIFE NEEDS ANSWERS, ROCHE OMNI, AUTOQC, Documents The universal system for Line Products FOB Gold Fecal. Hwever, Rche Diagnstics GmbH reserves the right t make any changes necessary withut ntice as part f nging prduct develpment. Any custmer mdificatin t the instrument will render the warranty r service agreement null and vid. Sftware updates are dne by Rche Service representatives. Cpyright 2009, Rche Diagnstics GmbH, all rights reserved The cntents f this dcument may nt be reprduced in any frm r cmmunicated t any third party withut the prir written cnsent f Rche Diagnstics. While every effrt is made t ensure its crrectness, Rche Diagnstics assumes n respnsibility fr errrs r missins which may appear in this dcument. Subject t change withut ntice. Instructins fr Use Revisin 4 cbas b 221 system Brands COBAS, COBAS B, LIFE NEEDS ANSWERS, ROCHE OMNI, AUTOQC, ROCHE MICROSAMPLER, COMBITROL and AUTO-TROL are trademarks f Rche. This manual has detailed descriptins f cbas b 221 system features and general peratinal cncepts, specificatin functins and use f cntrls, perating techniques, emergency prcedures, prduct labeling and maintenance prcedures. Hw t use this manual Keep this manual in a safe place t ensure that it is nt damaged and remains available fr use. This Instructins fr Use shuld be easily accessible at all times. T help yu find infrmatin quickly, there is a table f cntents at the beginning f the bk and each chapter. In additin, a cmplete index can be fund at the end. Where t find infrmatin In additin t the Instructins fr Use, the fllwing dcuments are als prvided t assist in finding desired infrmatin quickly: cbas b 221 system Reference Manual cbas b 221 system Shrt Instructin Cnventins used in this manual Visual cues are used t help lcate and interpret infrmatin in this manual quickly. This sectin explains frmatting cnventins used in this manual.

Where to Find Information In addition to the Service Manual, the following documents are also provided to assist in finding desired information quickly: o cobas b 221 system Instructions for Use o cobas b 221 system Operators CD o cobas b 221 system Reference Manual o cobas b 221 system Short Instruction o cobas b 221 system Service Manual (PDF or iSDoc version in GRIPS) o cobas b 221 system Spare Part List (PDF or iSDoc version in GRIPS) o Keep this manual in a safe place to ensure that it is not damaged and remains available for use.Roche Diagnostics May 2009 8 Service Manual Version 9.0 cobas b 221 system Conventions used in this manual Visual cues are used to help locate and interpret information in this manual quickly. This section explains formatting conventions used in this manual. Symbols The following symbols are used: e For more information about warning symbols, refer to the cobas b 221 system Intructions for Use. Biohazard Risk of infection. High Voltage Passages that are marked with this symbol warn of an immediate danger in connection with electrical wiring or components. ESD protection measures All sections or passages that are marked with this symbol warn of specific dangers in connection with static discharge. Packages that are marked with this symbol must only be opened by trained technical staff. Invisible Laser Radiation Avoid direct radiation to eyes Laser Class 3R according to EN 60825-1 P0 Recommended COBAS INTEGRA 400 plus - Roche Diagnostics (Schweiz) Direkt Kreatinin enzymatisch. Roche Elecsys, Cobas Abbott Architect, AxSym 17.05.2014 Documents cobas 8000 modular analyzer series Intelligent LabPower cobas 8000 modular analyzer series is the newest member of the Roche cobas modular platform family.. 6,000 5,000 8,000 7,000 9,000 050100 150200 250 300 Documents cobas b 221 system - Frank's Hospital Diagnostics April 2009 2 Instructions for Use Revision 10.

0 A-3 16 1 Safety infrmatin cbas b 221 system Cntents A-4 Instructins fr Use Revisin 10.0 17 cbas b 221 system 1 Safety infrmatin Imprtant infrmatin Imprtant infrmatin These Instructins fr Use cntain vital warnings and safety infrmatin. This instrument is intended t be used nly fr the specialized purpse described in the instructins. The mst imprtant prerequisites fr use, peratin, and safety are explained t ensure smth peratin. N warranty r liability claims will be cvered if the machine is used in ways ther than thse described r if the necessary prerequisites and safety measures are nt bserved. The instrument may be perated nly by persns whse qualificatins enable them t cmply with the safety measures that are necessary during peratin f the instrument. Suitable prtective equipment, like labratry clthing, prtective glves, prtective gggles and if necessary muth prtectrs, must be wrn t prevent direct cntact with bilgical wrking materials. In additin, a face mask is required if there is a risk. Adjustments and maintenance perfrmed with cvers remved and pwer cnnected may be attempted nly by a qualified technician wh is aware f the assciated dangers. Instrument repairs are t be perfrmed nly by the manufacturer r qualified service persnnel. Only accessries and supplies either delivered by r apprved by Rche are t be used with the instrument. These items are manufactured especially fr use with this instrument and meet the highest quality requirements. Operatin f the instrument with slutins whse cmpsitin is nt cnsistent with that f the riginal slutins can negatively affect the lng-term measurement accuracy. Deviatins in the cmpsitin f the slutins can als decrease the service life f the electrdes. In rder t ensure the quality f the measurement results, cmplete a quality cntrl test n 3 levels (lw, nrmal, high) after each electrde exchange, after each exchange f slutins and packs and after startup f the instrument.

Risk f infectin All sectins and parts f texts that are marked with this symbl describe prcedures that may invlve risk f infectin. IVD symbls The symbls are used in accrdance with DIN EN 980 (a) and DIN EN ISO 780 (b). Lt designatin Use by. The prduct shuld nt be used after expiry f the specified date. If a day is nt indicated, apply the last day f the respective mnth. Temperature limitatin The cnditins necessary t preserve the prduct's shelf life befre pening. Other symbls The fllwing symbls are listed as additinal infrmatin: Symbl Descriptin Electrdes: This date indicates the limit f the maximum strage time f an electrde. The electrde must be installed in the instrument n later than the imprinted date. If the installatin takes place n the imprinted date, it still falls within the specificatins. The calculatin f the Install befre date is based n the prductin date f the elctrde. Danger f sensitizatin during cntact with skin (when classified with R 43). Cautin: Avid cntact with eyes and skin, d nt inhale vaprs. Instructins fr Use Revisin 10 cbas b 221 system Symbl Descriptin Invisible Laser Radiatin Avid direct radiatin t eyes. Abbreviatins The fllwing abbreviatins are used: Abbreviatin A ANSI AQC B BG BUN C CLIA CLSI cnd CSA D dba DIL DNS E EC e.g. EN F FMS H Hct HIV HW Definitin American Natinal Standards Institute Autmatic Quality Cntrl Bld gas Abbr.This curve apprximates the audible range f the human ear. Instructins fr Use Revisin 12 cbas b 221 system 10 Instructins fr Use Revisin 10.0 13 Intrductin and specificatins A 1 Safety infrmatin A-3 2 General descriptins A-7 3 Installatin and shutdwn A-25 4 Specificatins A-57 5 Theretical fundatins A-95 14 15 cbas b 221 system 1 Safety infrmatin Cntents Safety infrmatin The infrmatin prvided in this chapter is essential fr the safe, truble-free peratin f the instrument and must be read and understd by the user. In this chapter Chapter 1 Imprtant infrmatin. 5 Operating safety infrmatin. 6 Instructins fr Use Revisin 10.

The ammnia ins can be determined using a ptentimetrical ammnia in-selective electrde. This measurement requires a reference electrde such as thse used in in-selective electrdes. Hematcrit: Measurement f the sample's cnductivity in the ISE measuring chamber. Calibratin prcedure thb and SO 2 was calibrated when the instrument was manufactured. Oxygen (O 2 ): PCO 2, ph, ISE: MSS: COOX: Ambient air and a zer pint slutin are used t calibrate xygen.Instructins fr Use Revisin 10.0 A-13 26 2 General descriptins cbas b 221 system Measurement evaluatin Measurement evaluatin The validity f the test results frm the cbas b 221 system must be carefully examined by a clinical-medical specialist wh will take the patient's clinical cnditin int cnsideratin befre any clinical decisins are reached based n the test results. The level have t be alternated (lw, nrmal, high).Safety instructins fr specific dangers Handling samples While handling samples, all necessary regulatins cncerning hygiene must be bserved. Dangerus pathgenic agents culd be present. Rche recmmends fllwing a decntaminatin prcedure in additin t regulatins specific t the labratry. These decntaminatin prcedures shuld be perfrmed peridically t minimize the risk f infectins. The temperature f the slutins shuld be adapted t the ambient temperature befre use. The shelf life f the slutins is limited. Please read the bttle label and the packaging fr the crrect strage temperature and the maximum shelf life. DO NOT FREEZE! If frzen, the slutin's cncentratin may change and cause calibratin errrs. D nt use damaged fluid packs (S2 and S3). D nt mix the individual cmpnents. Handling electrdes Stre the electrdes accrding t the packaging specificatins. The shelf life f the electrdes is limited. Please read the label and the packaging fr the crrect strage temperature and the maximum shelf life. CAUTION! Installatin nte fr the PCO 2 electrde Insert the electrde int the measuring chamber within 5 minutes f pening the ALU-PE packaging.

A special prtective gas atmsphere designed t cnditin the PCO 2 electrde during strage is fund inside the ALU-PE packaging. This gas atmsphere ensures immediate ptential stability during insertin f the electrde int the measuring chamber and immediate readiness fr measuring the first 2 pint calibratin. If mre than 5 minutes elapse after pening the ALU-PE packaging, the level f gas cnditining culd be lst and the time required fr the first-time calibratin culd be increased. Instructins fr Use Revisin 10.0 A-15 28 2 General descriptins cbas b 221 system General ntes n the use f the MSS cassette General ntes n the use f the MSS cassette Fr instrument versins with MSS mdule nly. Attentin: MSS cassette may nly be brught int cntact with liquids in the cbas b 221 system while electrdes are changed. Replace the MSS cassette within 28 days f installatin. After initial cntact with liquids, the MSS cassette may n lnger be remved frm the instrument. It may lead t the destructin f the enzyme sensrs. Strage: At 2 8 C, maximum f 2 weeks at rm temperature. MSS cassette remved frm the measuring chamber Once an MSS cassette is expsed t liquid, it must nt be allwed t dry ut under any circumstances since this wuld destry the enzymes. The enzymes are equipped with a special prtectant prir t shipping fr transprtatin purpses. This prtectant is washed ut inside the instrument during the warm-up phase and MSS plarizatin. Incmpatible substances The fllwing substances may nt be intrduced int the MSS measuring chamber under any circumstances since they wuld immediately destry the MSS sensrs r severely impact their functinality. A-16 Instructins fr Use Revisin 10.0 29 cbas b 221 system 2 General descriptins General ntes n the use f the MSS cassette Inserting the MSS cassette Hld the MSS cassette nly at the designated handle and avid tuching the cntacts.All infrmatin (results, errr messages, alarms, warnings, etc.) is displayed n the screen.

Additinally cmplete a quality cntrl test n ne level between tw autmatic 2P calibratins. The level have t be alternated (lw, nrmal, high). Since the measurements f the instrument depend nt nly n the crrect characteristic functin, but als n a series f marginal cnditins (e.g. pre-analysis), results btained frm the instrument shuld be submitted fr an expert pinin befre taking additinal measures based n the supplied measurements. Cautin (refer t accmpanying dcuments). Please refer t safety-related ntes in the manual accmpanying this instrument. In rder t preserve this cnditin and ensure safe peratin, the user must respect the ntices and warnings that are cntained in these Instructins fr Use. The instrument meets the cnditins fr cntaminatin level 2. D nt perate the instrument in an explsive envirnment r in the vicinity f explsive anesthetic mixtures cntaining xygen r nitrus xide. If bjects r liquids enter the internal areas f the instrument, remve the instrument frm its pwer supply and allw an expert t check it thrughly befre using it again. The instrument is suitable fr lng-term peratin indrs. The pwer crd must be plugged int a grunded pwer receptacle. When using an extensin crd, make sure it is prperly grunded. Any rupture f the grund lead inside r utside the instrument r a lse grund cnnectin may result in hazardus perating cnditins fr the perating persnnel. Intentinal discnnectin f the grunding is nt permitted. The instrument is nt suitable fr peratin with a direct current pwer supply. Use nly the riginal pwer plug delivered with the cbas b 221 system. The use f cntrls r adjustments r perfrmance f prcedures ther than thse specified herein may result in hazardus radiatin expsure. A-6 Instructins fr Use Revisin 10.0 19 cbas b 221 system 2 General descriptins Cntents General descriptins This chapter cntains a general descriptin f the instrument, as well as precautinary measures against special dangers and the prper handling f sensrs, slutins and the MSS cassette.

Instructins fr Use Revisin 10.0 A-9 22 2 General descriptins cbas b 221 system Intrductin During the measurement r calibratin r ther prcesses, it is pssible t cnduct database peratins, perfrm certain settings r call up general infrmatin at the same time.In rder t achieve accurate measurements f recmmended aqueus cntrl slutins (with regards t deviatins frm bilgical samples), chse the prper cmpnents and make the crrespnding crrectins in the QC measurement mde. Operating instructins The cbas b 221 system shuld be switched n at all times. If the instrument is switched ff fr an extended perid f time (mre than 24 hurs), a shutdwn must be perfrmed.Prevent any ther liquids frm entering the instrument except samples and QC material at the fill prt. The level have t be alternated (lw, nrmal, high).With Sftware V 6.0 nwards, using cbas bge link, the instrument can be mnitred frm ne lcatin, any disturbances can be remedied and the analytical quality mnitred.In rder t prevent multiple peratin f the instrument, n buttns n the screen shuld be pressed. A-12 Instructins fr Use Revisin 10.0 25 cbas b 221 system 2 General descriptins Measurement and calibratin prcedure Measurement and calibratin prcedure Measurement prcedure PO 2: Use f the Clark measurement principle: measurement f current generated by the reductin f xygen. The ptassium and calcium membranes cntain special neutral carriers. A special in exchanger is used fr chlride membranes. Calculatin f these variables als requires the use f a reference electrde a permanently cntacted chlride electrde in the cbas b 221 system. Glucse, lactate: Glucse xidizes t frm glucnlactn using atmspheric xygen and the glucse-xidase (GOD) enzyme, lactate xidizes t frm pyruvate using the lactate xidase enzyme. Urea: Urea is brken int ammnia and carbn dixide thrugh urease. Ammnia and carbn dixide react thrugh hydrlysis with physilgical ph t frm ammnia r bicarbnate ins.

The electrdes are flw-thrugh electrdes with a visible sample channel. Instructins fr Use Revisin 10.0 A-19 32 2 General descriptins cbas b 221 system System descriptin COOX mdule The COOX mdule cnsists f the hemlyzer and the COOX measuring chamber. The measurement is based n the principle f spectral phtmetry. Pumps Depending n the cnfiguratin, up t three peristaltic pumps transprt the sample and the perating fluids inside the instrument. A-20 Instructins fr Use Revisin 10.0 33 cbas b 221 system 2 General descriptins System descriptin Reverse side E A D B C A B C Pwer supply Main pwer switch and cnnectr Warning and identificatin labels D E Air filter Interfaces Figure A-5 Reverse side Pwer supply This unit als cntains the main pwer switch and the cnnectr. A B C D E F A Pwer supply B Service cnnectr C RS 232 D Ext. A-22 Instructins fr Use Revisin 10.0 35 cbas b 221 system 2 General descriptins System descriptin Barcde scanner Figure A-9 Barcde scanner Scanning f electrde data (type, lt, expiratin date) Scanning f patient r user identity Scanning f QC data (QC material, lt, basis, expiratin date, target values, etc.) Scanning f desired alphanumeric cde Press the buttn n the underside t activate the scanner. A beeping sund and a brief illuminatin f the LED n the upper side indicate the successful scanning f the barcde. Fr mre detailed infrmatin, please see enclsed manual f the PS2 hand-held scanner (included in scpe f delivery). Instructins fr Use Revisin 10.0 A-23 36 2 General descriptins cbas b 221 system System descriptin Warning and identificatin labels (incl. The sequence f the steps described must be strictly fllwed. When installing an instrument that was stred in a cl rm r was transprted at lw temperatures, be aware that cndensatin may have frmed and culd cause disturbances t the instrument. The instrument must be climatized at rm temperature fr at least ne hur befre beginning peratin. A-30 Instructins fr Use Revisin 10.

0 43 cbas b 221 system 3 Installatin and shutdwn Installatin 2. Pwer supply 1 Place the pwer supply, including the tw adapter cnnectrs, n the hlder and psitin them. A B B A Screw B Hlder Figure A-14 Pwer supply 2 Tighten the screw. 3. Attach pwer crd and barcde scanner 1 Cnnect the pwer crd. 2 Cnnect the barcde scanner, and, if necessary, the netwrk cnnectin t the apprpriate prt n the rear side f the cbas b 221 system. 4. Switch n Switch the instrument n and wait until the prgram has cmpletely laded and started. Befre starting the installatin, yu must set the language, in which the unit is t be perated, the date and the time. Instructins fr Use Revisin 10.0 A-31 44 3 Installatin and shutdwn cbas b 221 system Installatin 5. Installatin When carrying ut the installatin, fllw the n-screen instructins. Installatin must be carried ut cmpletely and may nt be interrupted. Observe the listed sequence while perfrming the actins. If the autmatic first installatin is unsuccessful, yu must carry ut the installatin prcess manually.The time scale uses markers t shw the selected interval fr the 2P calibratin and the start time fr the system calibratin. Intervals: System calibratin 2P calibratin 1P calibratin Every 8, 12 r 24 hurs. Every 4, 8 r 12 hurs. This actin is perfrmed autmatically. Valve V19 is pushed in t prevent the tube frm being pinched while the aluminum part is tightened. A B A VM B V19 Figure A-18 Valve VM 3 Clse dcking mechanism and bttle cmpartment cver. A-34 Instructins fr Use Revisin 10.0 47 cbas b 221 system 3 Installatin and shutdwn Installatin 12. D nt bend the insert needle during this prcess. A A Needle Figure A-19 Insert needle 5 Rtate the fill prt 90 clckwise and upwards until it snaps int place.Check the crrect psitining f the sample inlet path t the bypass nipple (see belw). A-36 Instructins fr Use Revisin 10.0 49 cbas b 221 system 3 Installatin and shutdwn Installatin 13. Insert printer paper The printer paper is heat sensitive n ne side nly.

Observe the crrect insertin f the thermal paper rll. A B A Paper lid B Printer lever Figure A-25 Insert printer paper - withut take-up unit Figure A-26 Insert printer paper - with take-up unit (ptinal) 6 The paper is autmatically pulled int the printer. 7 Clse paper lid. With take-up unit (ptinal) 1 Press the paper feed buttn until the paper is lng enugh. 2 Insert the beginning f the paper in the take-up unit accrding t the instructins n the inside f the paper lid.During peratin, the paper shuld be tautened nw and then by turning the take-up rller. 3 Clse printer cver. A-38 Instructins fr Use Revisin 10.0 51 cbas b 221 system 3 Installatin and shutdwn Installatin 14. Insert peristaltic pump tubes 1 Open the peristaltic pump's clear plastic cver (tensin lever). 2 Push the linear bracket (white plastic part) upwards (see belw). Instructins fr Use Revisin 10.0 A-39 52 3 Installatin and shutdwn cbas b 221 system Installatin 16. Open the AutQC drawer and remve the AutQC valve clamp 1 Pull ut the AutQC drawer. 2 Pull the key f the AutQC valve up and ut (see belw). This actin is perfrmed autmatically. 18. Open AutQC drawer and insert ampule hlder 1 Pull the AutQC drawer ut again. In each case, pen nly the relevant measuring chamber. Keep the bttle cmpartment cver clsed. A-40 Instructins fr Use Revisin 10.0 53 cbas b 221 system 3 Installatin and shutdwn Installatin The fllwing screen appears: Figure A-31 Changing f electrdes 2 Open the lcking lever.Check the internal electrlyte f the electrdes fr pssible air bubbles (see belw). If there are air bubbles between the cntact pin and the membrane, there will nt be effective electrical cnductin. Result: calibratin and measurement errrs! 4 Remve any air bubbles. Remve air bubbles by hlding the electrde vertically and by tapping lightly with a fingernail against the electrde bdy (see belw). A A Free f air bubbles. Figure A-32 Electrde 5 Insert the electrdes, beginning at the right and prceeding left accrding t the clr cde.

6 Push all electrdes slightly t the right s that they are lined up tgether withut gaps. Instructins fr Use Revisin 10.0 A-41 54 3 Installatin and shutdwn cbas b 221 system Installatin a Insertin f the reference electrde 1 Insert the reference electrde. Figure A-33 Reference electrde 2 Insert the reference tube int the upper tube guide channel f the left lcking lever and int the tube hlder f the cver hinge. Clse the lcking lever (see belw). A A Lcking lever Figure A-34 Insertin f the reference electrde 3 Cnnect the white cnnectr n the end f the tube t the measuring chamber cassette (see belw). A B A Cnnectr B Measuring chamber cassette Figure A-35 Insertin f the reference electrde 2 4 Scan the barcdes lcated n the inner packaging f each electrde r enter the barcdes manually with the help f the keybard. 5 Clse the measuring chamber cver. A-42 Instructins fr Use Revisin 10.0 55 cbas b 221 system 3 Installatin and shutdwn Installatin a MSS measuring chamber (fr instrument versins with MSS mdule nly) Hld the MSS cassette nly at the designated handle and avid tuching the cntacts. 1 Open the cver f the MSS measuring chamber (apply frce t the right edge f the MC cver with a finger t push it t the left and pen up the MC cver). Having cmpleted the installatin prcess, the unit requests a bld sample. Remve packs rubber sealings. 4 Push the tw packs int the apprpriate lcatin in accrdance with the labeling n the dcking mechanisms until the packs lck. T avid splashing the S1 Rinse Slutin, deaerate the bttle at abut 3000 m abve sea level r higher befre inserting it. 6 Place the bttle tl n the screw cap f the S1 Rinse Slutin (see belw). A B Figure A-41 Open bttle Instructins fr Use Revisin 10.0 A-45 58 3 Installatin and shutdwn cbas b 221 system Installatin 21. Autmatic sequences take place and the unit warms up. 2 Installatin is cmplete. If a pwer failure ccurs during installatin, the installatin starts anew with the next restart.

Actins which were perfrmed successfully are discarded. 22. Perfrm MSS plarizatin (cbas b 221 system and cbas b 221 system nly) 1 Prepare a syringe r capillary with whle bld fr plarizatin. Figure A-42 MSS plarizatin 2 The bld sample is inserted via fill prt similar t a measurement.A-46 Instructins fr Use Revisin 10.0 59 cbas b 221 system 3 Installatin and shutdwn Installatin 23. A wrng barmeter value leads t wrng PO 2 measurement results. Quality cntrl 1 Define the material and if an AutQC drawer (ptin) is available insert the mats befre perfrming a quality cntrl measurement.Make sure that the results agree with the target values. Fllw the instructins n the screen. If the instrument is turned n again, a new MSS cassette must be inserted.Lnger than 24 hurs If the cbas b 221 system will be shut dwn fr lnger than 24 hurs, perfrm the fllwing prcedure. Befre perfrming a shutdwn, Rche Diagnstics recmmends decntaminating all surfaces and tube paths. The prcedure ends in switching ff the instrument. Prcessing the actins: Manual: Autmatic: The crrespnding line f the list bx cntains an instructin which must be perfrmed manually. A-48 Instructins fr Use Revisin 10.0 61 cbas b 221 system 3 Installatin and shutdwn Shutdwn Upn successful cmpletin, this symbl is displayed. 1. Open bttle cmpartment cver and nly remve bttle S1 and packs (depending n the cnfiguratin S2 and S3). 1 Open bttle cmpartment cver and dcking mechanism and remve bttle S1 and the packs (S2 and S3). D nt remve the waste cntainer! 2 Clse dcking mechanism and bttle cmpartment cver. 2. Fill the shutdwn kit with distilled water Fill the shutdwn kit abut halfway with distilled water. D nt bend the needle. Bth valves are pushed ut. 14. Release screws at V19 (bttle cmpartment) 1 Open the bttle cmpartment cver and the dcking mechanism S3. 2 Lsen the screws (A) f the aluminum part f valve V19 (apprx. 2-3 turns). A A V 19 A Screws Figure A-50 Valve V19 3 Clse the dcking mechanism S3 and the bttle cmpartment cver. 15.